Mutations in TP53 occur commonly in the majority of human tumors and confer aggressive tumor phenotypes. including metastasis and therapy resistance. CB002 and structural-analogs restore p53 signaling in tumors with mutant-p53 but we find that unlike other xanthines such as caffeine. pentoxifylline. https://www.roneverhart.com/ASUS-VivoBook-X515-15-6-FHD-Laptop-Intel-Core-i5-1135G7-2-4-GHz-Intel-Iris-Xe-Graphics-16GB-DDR4-RAM-1TB-SSD-Windows-/