Background: Tumor markers were used in malignant pleural effusion with negative cytology. Aim of the work: The aim was to assess the value of serum and pleural levels of cyfra 21-1 (fragment of cytokeratin 19) and carcinoembryonic antigen (CEA) in the diagnosis of malignant pleural effusion. Patients and methods: This study was conducted on 48 patients divided into group I (benign eff... https://www.rawafricaonline.com/